Method of generating a gradient flow having a constant compositional noise characteristic
US10132306B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 3, 2015 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Nov 26, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/34
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described is a method of generating a flow having a composition gradient. A plurality of pump strokes is generated for each pump in a plurality of pumps. Each pump stroke has an initiation time and provides a volume contribution of a liquid to be mixed in the flow according to the composition gradient for the flow. The pump strokes of the pumps are controlled so that a sum of the volume contributions of the liquids that occurs between consecutive initiations of one of the pumps is maintained at a constant value throughout the duration of the flow. For each pump, the flow rates and the times between stroke initiations can change as long as the sum of all volumes contributed between the consecutive initiations of one of the pumps is held constant. Advantageously, the method achieves a constant compositional noise characteristic throughout the duration of the flow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.