Method of assessing breast density for breast cancer risk applications
US10134148B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 30, 2014 |
| Grant date | Nov 20, 2018 |
| Priority date | — |
| Expiry date | Nov 25, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30068
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Breast density is a significant breast cancer risk factor measured from mammograms. Disclosed is a methodology for converting continuous measurements of breast density and calibrated mammograms into a four-state ordinal variable approximating the BI-RADS ratings. In particular, the present disclosure is directed to a calibration system for a specific full field digital mammography (FFDM) technology. The calibration adjusts for the x-ray acquisition technique differences across mammograms resulting in standardized images. The approach produced various calibrated and validated measures of breast density, one of which assesses variation in the mammogram referred to as Vc (i.e. variation measured from calibrated mammograms). The variation in raw mammograms [i.e. Vr] is a valid breast density risk factor in both FFDM in digitized film mammograms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.