Vitrification of biological material

US10136636B2 · kind B2 · utility

Assignee

• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• David Lai · Ann Arbor, US
• Shuichi Takayama · Ann Arbor, US
• Gary D. Smith · Ann Arbor, US
• Jun Ding · Ann Arbor, US

Key dates

• Filing date: Oct 14, 2014
• Grant date: Nov 27, 2018
• Expiry date: Oct 14, 2034

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/0478
• WIPO field: Basic materials chemistry
• WIPO sector: Chemistry

Abstract

Microfluidic cryopreservation technology is provided and particularly, but not exclusively, devices, systems, and methods for cryopreservation of biological materials such as oocytes, zygotes, and embryos. The present microfluidic devices and related systems and methods are configured to maintain biological material in a housing chamber when subjected to a constant volumetric flow of fluid of changing fluid density.