Microneedle arrays for biosensing and drug delivery

US10136846B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• North Carolina State University · US
• National Technology & Engineering Solutions of Sandia, LLC · US

Inventors

• Joseph Wang · San Diego, US
• Joshua Ray Windmiller · Del Mar, US
• Roger Narayan · Raleigh, US
• Phillip Miller · O'Fallon, US
• Ronen Polsky · Albuquerque, US
• Thayne L. Edwards · Bend, US

Key dates

• Filing date: Aug 25, 2017
• Grant date: Nov 27, 2018
• Expiry date: Aug 25, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2037/003
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods, structures, and systems are disclosed for biosensing and drug delivery techniques. In one aspect, a device for detecting an analyte and/or releasing a biochemical into a biological fluid can include an array of hollowed needles, in which each needle includes a protruded needle structure including an exterior wall forming a hollow interior and an opening at a terminal end of the protruded needle structure that exposes the hollow interior, and a probe inside the exterior wall to interact with one or more chemical or biological substances that come in contact with the probe via the opening to produce a probe sensing signal, and an array of wires that are coupled to probes of the array of hollowed needles, respectively, each wire being electrically conductive to transmit the probe sensing signal produced by a respective probe.