Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives

US10138236B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Susanne Röhrig · Hilden, DE
• Alexander Hillisch · Solingen, DE
• Stefan Heitmeier · Wülfrath, DE
• Martina Victoria Schmidt
• Karl-Heinz Schlemmer · Wuppertal, DE
• Adrian Tersteegen · Wuppertal, DE
• Martina Schäfer · Berlin, DE
• Henrik Teller · Schwaan, DE
• Eloisa JIMENEZ NUNEZ · Wuppertal, DE

Key dates

• Filing date: Sep 22, 2015
• Grant date: Nov 27, 2018
• Expiry date: Sep 22, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to substituted pyridobenzazepine and pyridobenzazocine derivatives and to processes for preparation thereof, and also to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and oedemas, and also ophthalmic disorders.