Peptide ligands for hepatic stellate cells
US10138273B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2016 |
| Grant date | Nov 27, 2018 |
| Priority date | — |
| Expiry date | Oct 7, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for identifying and using polypeptides that target hepatic stellate cells are described. Embodiments include a targeting composition that may include one or more polypeptides including an amino acid sequence that binds to an insulin-like growth factor 2 receptor. Other embodiments relate to targeting systems that may include a one or more polypeptides including an amino acid sequence that binds to an insulin-like growth factor 2 receptor of hepatic stellate cells. Further embodiments relate to methods for treating health disorders in which the methods include the targeting composition or targeting systems as well as an agent capable of treating the disorder.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.