Bio-production of lentiviral vectors
US10138495B2 · kind B2 · utility
2Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 2, 2017 |
| Grant date | Nov 27, 2018 |
| Priority date | — |
| Expiry date | Nov 2, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides a method of generating a stable producer cell line. The generation of stable producer cell lines, such as those provided in accordance with the present invention, increases the reproducibility and ease of creating high titer lentiviral stocks while easing biosafety concerns and the variation in expressed envelope proteins defines the tropism of the generated virus. The present disclosure also provides for a novel lentiviral transfer vector plasmid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.