Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
US10143654B2 · kind B2 · utility
2Cited by
55References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2016 |
| Grant date | Dec 4, 2018 |
| Priority date | — |
| Expiry date | Dec 7, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Controlled-release therapeutic compositions including melatonin combined with sedative and/or analgesic ingredients are described. The compositions have a solid core including melatonin in an acidified polymeric matrix. A sedative ingredient such as GABA receptor agonist may also be in the acidified polymeric matrix. The composition may include an expedited release portion providing a burst release of active ingredients and a sustained release portion providing a sustained release of active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.