Hydroxy-substituted amino and ammonium derivatives and their medical use

US10143668B2 · kind B2 · utility

Assignee

• GRI BIO, INC. · US

Inventors

• Georg Schlechtingen · Dresden, DE
• Hans-Joachim Knolker · Dresden, DE
• Tim Friedrichson · Dresden, DE
• Gary Jennings · Dresden, DE
• Tobias Braxmeier · Gaggenau, DE

Key dates

• Filing date: Feb 17, 2017
• Grant date: Dec 4, 2018
• Expiry date: Feb 17, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C237/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.