Labelled nucleotides
US10144754B2 · kind B2 · utility
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111References
23Claims
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Key dates
| Filing date | Jul 6, 2016 |
| Grant date | Dec 4, 2018 |
| Priority date | — |
| Expiry date | Jul 6, 2036 |
Classification
- Technology area (CPC —)General
Abstract
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.