Patent · US Active

Semi-continuous process for the production of rhamnolipids at high yield and titer

US10144943B2 · kind B2 · utility

2Cited by
4References
40Claims
0Family size

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Inventor

Key dates

Filing dateMay 4, 2016
Grant dateDec 4, 2018
Priority date—
Expiry dateMay 13, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P19/44
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Provided is a semi-continuous fermentation method of a rhamnolipid producing microorganism to produce rhamnolipids. The fermentation may be run as a batch process but at the end of the fermentation, at least about 70% of the fermentation medium comprising one or more rhamnolipids is drawn out and the new culture medium (feedstock) is fed in as a replacement. This process may be repeated for at least about one month without having to sacrifice RL yield and titer. It allows the fermenter to be utilized at a higher capacity with less downtime for clean-up compared to batch and fed batch fermentation strategies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.