Patent · US Active

Optimized real time nucleic acid detection processes

US10144957B2 · kind B2 · utility

1Cited by
114References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 30, 2016
Grant dateDec 4, 2018
Priority date
Expiry dateJan 20, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/708
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This invention provides for compositions for use in real time nucleic acid detection processes. Such real time nucleic acid detection processes are carried out with energy transfer elements attached to nucleic acid primers, nucleotides, nucleic acid probes or nucleic acid binding agents. Real time nucleic acid detection allows for the qualitative or quantitative detection or determination of single-stranded or double-stranded nucleic acids of interest in a sample. Other processes are provided by this invention including processes for removing a portion of a homopolymeric sequence, e.g., poly A sequence or tail, from an analyte or library of analytes. Compositions useful in carrying out such removal processes are also described and provided. Paneling and multiplex analyses of more than one nucleic acid analyte using one sample are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.