Patent · US Active

Isoxazole derivatives as FXR agonists and methods of use thereof

US10149835B2 · kind B2 · utility

2Cited by
9References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 17, 2017
Grant dateDec 11, 2018
Priority date
Expiry dateMay 17, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D261/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR and methods for their preparation and use.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.