Optogenetic control of endothelial cells
US10149986B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Jun 26, 2017 |
| Grant date | Dec 11, 2018 |
| Priority date | — |
| Expiry date | Jun 26, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2799/021
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention features methods for regulating vascular properties by controlling the membrane properties of endothelial cells using optogenetics and light. The invention features methods to transport therapeutics across the vascular barrier into tissues such as the brain and the lung, with high spatial and temporal precision, and for controlling vascular properties such as vascular tone, arterial diameter, and vascular growth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.