Multimeric IL-15 soluble fusion molecules and methods of making and using same
US10150805B2 · kind B2 · utility
41Cited by
8References
20Claims
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Key dates
| Filing date | Mar 29, 2016 |
| Grant date | Dec 11, 2018 |
| Priority date | — |
| Expiry date | Mar 29, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.