Methods for preparing monoclonal antibodies recognizing glycan binding site as an epitope
US10150961B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jul 19, 2013 |
| Grant date | Dec 11, 2018 |
| Priority date | — |
| Expiry date | Jan 31, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B30/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to a method for producing a monoclonal antibody that binds to an epitope for the glycan binding site of a glycoprotein. According to the present disclosure, a monoclonal antibody that recognizes the glycan binding site of a glycoprotein as an epitope can be produced in a relatively simple and economic manner, and a monoclonal antibody having high sensitivity and specificity for the glycan binding site of a glycoprotein can be produced. The monoclonal antibody produced according to the present disclosure can be effectively used as an agent for diagnosing or treating various diseases associated with a change in glycan structure or glycan expression level.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.