Selection by compartmentalized screening
US10151698B2 · kind B2 · utility
29Cited by
0References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2017 |
| Grant date | Dec 11, 2018 |
| Priority date | — |
| Expiry date | Dec 27, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/6458
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsules; and identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.