Norepinephrine compositions and methods therefor

US10159657B2 · kind B2 · utility

Assignee

• NEUVANA, LLC · US

Inventors

• Vivek Yadav · Henderson, US
• Sriramya Garapati · New Brunswick, US
• Tushar Hingorani · Bound Brook Junction, US
• Iouri V. Ilitchev
• Prem Sagar Akasapu · Edison, US
• Kumaresh Soppimath · Colts Neck Township, US
• Navneet Puri · Lebanon, US

Key dates

• Filing date: Apr 10, 2018
• Grant date: Dec 25, 2018
• Expiry date: Apr 10, 2038

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably, compositions presented herein are substantially antioxidant free and exhibit less than 10% isomerization of R-nor epinephrine and exhibit less than 5% degradation of total norepinephrine.