Pharmaceutical compositions for preventing glucocorticoid-induced corneal thinning
US10159684B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 8, 2017 |
| Grant date | Dec 25, 2018 |
| Priority date | — |
| Expiry date | Jun 8, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0014
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to method and pharmaceutical compositions for preventing glucocorticoid-induced corneal or skin thinning. In particular, the present invention relates to a mineralocorticoid receptor antagonist for topical use in a method for preventing or reducing glucocorticoid-induced corneal or skin thinning in a subject in need thereof. The invention also relates to a topical pharmaceutical composition comprising an amount of at least one glucocorticoid and an amount of at least one mineralocorticoid receptor antagonist or inhibitor of MR expression for use in a method for treating an inflammatory skin disease or an inflammatory disease of the cornea or of the anterior segment of the eye in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.