HER2 binders

US10159760B2 · kind B2 · utility

Assignee

• General Electric Company · US

Inventors

• Faisal Ahmed Syud · Clifton Park, US
• Brian Duh-Lan Lee · Rexford, US
• Rong Zhang · Zhejiang, CN
• Peter Brian Iveson · Norton, GB
• Paul Schaffer · Vancouver, CA
• Tove Simonsson · Lund, SE
• Elin Gunneriusson · Hallsberg, SE
• Fredrik Frejd · Stockholm, SE
• Lars Abrahmsen · Bromma, SE
• Joachim Feldwisch · Tyresö, SE
• Nina Herne · Stockholm, SE
• Christofer Lendel · Älta, SE

Key dates

• Filing date: Mar 29, 2016
• Grant date: Dec 25, 2018
• Expiry date: Aug 12, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/71
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Imaging agents comprising an isolated polypeptide conjugated with a radionucleide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.