Coumarin dyes and conjugates thereof

US10160861B2 · kind B2 · utility

Assignee

• CYANAGEN S.r.l. · IT

Inventors

• Thomas Paul JANSEN · Kohlenbissen, DE
• Giacomo Rodeghiero · Bologna, IT
• Dario Foglietta · Lugo, IT
• Rossana PERCIACCANTE · Granarolo dell'Emilia, IT
• Leopoldo Della Ciana · Bologna, IT

Key dates

• Filing date: Mar 14, 2017
• Grant date: Dec 25, 2018
• Expiry date: Mar 14, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/52
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention describes novel 7-alkylamino-3-(thienyl) coumarin fluorescent dyes of formula (I)These dyes are water soluble, can be excited by the 405 nm excitation source and exhibit a large Stokes shift (≥80 nm). Furthermore, the dyes possess a reactive group for the labeling of biomolecules or other analytes.