Patent · US Active

Factor VII polypeptides that are modified and uses thereof

US10160961B2 · kind B2 · utility

2Cited by

42References

26Claims

0Family size

Assignee

Catalyst Biosciences, Inc. · US

Inventors

Edwin L. Madison · Dallas, US
Christopher D. Thanos · Tiburon, US

Key dates

Filing date	Sep 7, 2016
Grant date	Dec 25, 2018
Priority date	—
Expiry date	Apr 25, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Nucleic acid encoding modified factor VII polypeptides, vectors and cells containing the nucleic acid, uses of the nucleic acids, methods of making the encoded polypeptides, and methods of treatment are provided. The encoded modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among the encoded modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.