Patent · US Active

Lipids and lipid nanoparticle formulations for delivery of nucleic acids

US10166298B2 · kind B2 · utility

56Cited by

49References

39Claims

0Family size

Assignee

Acuitas Therapeutics, Inc. · CA

Inventors

Steven M. Ansell · Vancouver, CA
Xinyao Du · Richmond, CA

Key dates

Filing date	Oct 28, 2016
Grant date	Jan 1, 2019
Priority date	—
Expiry date	Oct 28, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y113/12007
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, L1, L2, G1, G2 and G3 are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.