Pharmaceutical composition for treating cerebrovascular diseases, containing stem cell-derived exosome as active ingredient
US10167448B2 · kind B2 · utility
1Cited by
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5Claims
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Key dates
| Filing date | Dec 12, 2014 |
| Grant date | Jan 1, 2019 |
| Priority date | — |
| Expiry date | Jun 20, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/734
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a pharmaceutical composition for treating cerebrovascular diseases including stem cell-derived exosomes as an active ingredient. The stem cell-derived exosomes according to the present invention have superior nerve cell protective effects, such as inhibition of cerebral ventricular distention, reduction of hydrocephalus, and inhibition of nerve cell death and cellular inflammation in an intraventricular hemorrhage (IVH) animal model, and thus, can be useful in treating cerebrovascular diseases including intraventricular hemorrhage, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.