Detection of genetic abnormalities
US10167508B2 · kind B2 · utility
0Cited by
120References
29Claims
0Family size
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Key dates
| Filing date | Feb 29, 2012 |
| Grant date | Jan 1, 2019 |
| Priority date | — |
| Expiry date | Apr 3, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides assay systems and related methods for determining genetic abnormalities in mixed samples comprising cell free DNA from both normal and putative genetically atypical cells. Exemplary mixed samples for analysis using the assay systems of the invention include samples comprising both maternal and fetal cell free DNA and samples that contain DNA from normal cells and circulating cancerous cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.