Compositions and methods for capture of cellular targets of bioactive agents
US10168323B2 · kind B2 · utility
3Cited by
13References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 11, 2014 |
| Grant date | Jan 1, 2019 |
| Priority date | — |
| Expiry date | Mar 11, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5005
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture dimers), surfaces (e.g., displaying, capture ligands, capture proteins, or capture dimers), and methods of capturing and identifying the cellular targets of a bioactive agent therewith.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.