Formulations and carrier systems including compound interactive domains

US10172795B2 · kind B2 · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Xiang Gao · San Jose, US
• Song Li · Beijing, CN
• Peter Wipf · Pittsburgh, US
• Michael W. Epperly · Pittsburgh, US
• Joel S. Greenberger · Dorpsstraat, US

Key dates

• Filing date: Dec 12, 2013
• Grant date: Jan 8, 2019
• Expiry date: Dec 12, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least one compound interactive domain comprising the at least one group that interacts with the compound with at least one hydrophilic domain, and combining the compound and the carrier agent to create the formulation. Creating the carrier agent may further include conjugating the at least one compound interactive domain with at least one hydrophobic domain so that the at least one compound interactive domain is positioned between the at least one hydrophilic domain and the at least one hydrophobic domain.