Patent · US Active

Crystal forms of scutellarin aglycone and preparation thereof

US10172824B2 · kind B2 · utility

1Cited by

0References

7Claims

0Family size

Assignees

Yunnan Institute of Materia Medica · CN
HLK PHARMACEUTICALS CO., LTD. · CN

Inventors

Zeren Wang · Longchuan, CN
Jun Xu · Gaithersburg, US
Minghui Wang · Beijing, CN
Zhaoyun Zhu · Longchuan, CN
Jingkun Wang · Longchuan, CN
Shuangxi MEI · Longchuan, CN
Wenqiang Sun · Longchuan, CN
Tao Cui · Longchuan, CN

Key dates

Filing date	Dec 2, 2015
Grant date	Jan 8, 2019
Priority date	—
Expiry date	Dec 2, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D311/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention belongs to the field of medicine and chemical industry, and particularly relates to multiple crystal forms of scutellarin aglycone and preparation thereof. The invention also relates to use of said crystal forms of scutellarin aglycone in the manufacture of a medicament for preventing and/or treating a cardiovascular or cerebrovascular disease, rheumatic arthritis or stroke sequelae, etc. The crystal forms of scutellarin aglycone according to the invention have good stability, and can solve the problems concerning poor oral absorption and low bioavailability of scutellarin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.