Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors
US10172845B2 · kind B2 · utility
3Cited by
77References
29Claims
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Key dates
| Filing date | Jan 3, 2018 |
| Grant date | Jan 8, 2019 |
| Priority date | — |
| Expiry date | Jan 3, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compounds of the Formula I: or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.