XTEN conjugate compositions and methods of making same
US10172953B2 · kind B2 · utility
10Cited by
12References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 2013 |
| Grant date | Jan 8, 2019 |
| Priority date | — |
| Expiry date | Aug 29, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to extended recombinant polypeptide (XTEN) compositions, conjugate compositions comprising XTEN and XTEN linked to cross-linkers useful for conjugation to pharmacologically active payloads, methods of making highly purified XTEN, methods of making XTEN-linker and XTEN-payload conjugates, and methods of using the XTEN-cross-linker and XTEN-payload compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.