Systems for stabilizing and delivering active agents
US10172959B2 · kind B2 · utility
4Cited by
53References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 2017 |
| Grant date | Jan 8, 2019 |
| Priority date | — |
| Expiry date | Mar 1, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A delivery system for active agents, and methods of making and using the systems, are provided. The delivery systems have (i) a ligand that is selective for an endogeneous plasma protein in the serum of a subject; and, (ii) a linker configured for operatively attaching the ligand covalently to an active agent to increase the half-life of the active agent in the serum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.