Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors
US10174027B2 · kind B2 · utility
12Cited by
77References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 2017 |
| Grant date | Jan 8, 2019 |
| Priority date | — |
| Expiry date | Dec 29, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.