Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
US10174085B2 · kind B2 · utility
1Cited by
8References
23Claims
0Family size
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Key dates
| Filing date | Nov 13, 2017 |
| Grant date | Jan 8, 2019 |
| Priority date | — |
| Expiry date | Nov 13, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.