Patent · US Active

Highly galactosylated anti-TNF-α antibodies and uses thereof

US10174110B2 · kind B2 · utility

3Cited by
70References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 13, 2014
Grant dateJan 8, 2019
Priority date
Expiry dateMay 1, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the disclosure relates to highly galactosylated anti-TNF-alpha antibodies and compositions thereof. In one aspect, the disclosure relates to populations of anti-TNF-alpha antibodies with a high level of galactosylation, and compositions thereof. In one aspect, the disclosure relates to methods of production and use of highly galactosylated anti-TNF-alpha antibodies and populations of anti-TNF-alpha antibodies with a high level of galactosylation. In some embodiments, the anti-TNF-alpha antibody is adalimumab.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.