Hyperbranched polyester with a hydrophobic nucleus for solubilizing poorly soluble active substances

US10174156B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Holger Türk · Mannheim, DE
• Monika Haberecht · Ludwigshafen, DE
• Hiroe Yamada · Saarburg, DE
• Bernd Bruchmann · Ludwigshafen, DE
• Daniel Schönfelder · Brussels, BE
• Michael Ishaque · Mannheim, DE
• Ulrike Troppmann · Schifferstadt, DE
• Joachim Clauss · Scheinfeld, DE
• Chee Chin Liew · Bad Dürkheim, DE

Key dates

• Filing date: Dec 15, 2010
• Grant date: Jan 8, 2019
• Expiry date: Jun 10, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a composition comprising an active ingredient with a maximum solubility in water at 20° C. of 10 g/l, and a hyperbranched polyester based on a hydrophobic dicarboxylic acid and a trifunctional alcohol. The invention further relates to the hyperbranched polyester mentioned, to a process for preparation thereof and to the use thereof for solubilizing an active ingredient with a maximum solubility in water at 20° C. of 10 g/l in aqueous solutions.