Sodium channel modulators for the treatment of pain

US10179781B2 · kind B2 · utility

Inventors

• Olga BABICH · Cranford, US
• Robert Zhiyong Luo · New City, US
• Yanlin WANG-FISCHER · Fryeburg, US
• David Palling · Glen Ridge, US
• Srinivasan P. Venkatachalan · Monmouth Junction, US

Key dates

• Filing date: Mar 13, 2014
• Grant date: Jan 15, 2019
• Expiry date: Mar 13, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are sodium channel modulating Compounds, in particular NaV1.7 modulating compounds of Formula I:In particular, provided herein are processes for the preparation of, intermediates used in the preparation of, pharmaceutical compositions comprising, and therapeutic methods comprising administering such compounds. In particular, provided herein are compounds for the treatment of pain.