Patent · US Active

Systems and methodologies for proton computed tomography

US10180505B2 · kind B2 · utility

1Cited by
105References
20Claims
0Family size

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Key dates

Filing dateJul 15, 2015
Grant dateJan 15, 2019
Priority date
Expiry dateMar 21, 2036

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2223/419
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed are systems, devices and methodologies relating to proton computed tomography. In some implementations, detection of protons can yield track information before and after an object for each proton so as to allow determination of a likely path of each proton within the object. Further, measurement of energy loss experienced by each proton allows determination that a given likely path results in a given energy loss. A collection of such data allows characterization of the object. In the context of energy loss, such a characterization can include an image map of relative stopping power of the object. Various reconstruction methodologies for obtaining such an image, including but not limited to superiorization of a merit function such as total variation, are disclosed. In some implementations, various forms of total variation superiorization methodology can yield excellent results while being computationally efficient and with reduced computing time. In some implementations, such a methodology can result in high quality proton CT images using relatively low dose of protons.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.