Patent · US Active

Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer

US10181008B2 · kind B2 · utility

1Cited by

2References

17Claims

0Family size

Assignee

Genomic Health, Inc. · US

Inventors

Steven Shak · Burlingame, US
George Andrew WATSON · Los Altos, US
Michael Crager · Menlo Park, US
Tara Maddala · Sunnyvale, US
Margarita LOPATIN · Palo Alto, US
Audrey Goddard · San Francisco, US
Dejan Knezevic · Palo Alto, US
Christer Svedman · Stockholm, SE

Key dates

Filing date	May 29, 2014
Grant date	Jan 15, 2019
Priority date	—
Expiry date	Jan 15, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldComputer technology
WIPO sectorElectrical engineering

Abstract

The present invention provides algorithm-based molecular assays that involve measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The present invention also provides methods of obtaining a quantitative score for a patient with kidney cancer based on measurement of expression levels of genes from a biological sample obtained from a kidney cancer patient. The genes may be grouped into functional gene subsets for calculating the quantitative score and the gene subsets may be weighted according to their contribution to cancer recurrence.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.