Lipid membrane structure for intracellular delivery of siRNA
US10182987B2 · kind B2 · utility
3Cited by
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19Claims
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Key dates
| Filing date | May 18, 2015 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Aug 21, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/63
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lipid membrane structure encapsulating an siRNA inside thereof and containing a lipid compound of the formula (I) as a lipid component (R1 and R2 represent CH3—(CH2)n—CH═CH—CH2—CH═CH—(CH2)m—, n represents an integer of 3 to 5, m represents an integer of 6 to 10, p represents an integer of 2 to 7, and R3 and R4 represent a C1-4 alkyl group or a C2-4 alkenyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.