2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof
US10183010B2 · kind B2 · utility
0Cited by
3References
5Claims
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Key dates
| Filing date | Jan 27, 2016 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Jan 27, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the technical field of medicinal chemistry, and in particular discloses a 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof. The compound and pharmaceutically acceptable salt, isomer, racemate, prodrug, co-crystallized complex, hydrate, and solvate thereof can effectively inhibit the BET bromodomain receptor, and can be used for preparing a medicine for treating cancers, cell proliferative disorders, inflammatory diseases, and autoimmune disorders, sepsis, and viral infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.