Cationic oil-in-water emulsions
US10183074B2 · kind B2 · utility
7Cited by
31References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 23, 2017 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Mar 23, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.