Tricyclic compounds and uses thereof in medicine
US10183917B2 · kind B2 · utility
2Cited by
14References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2016 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Feb 5, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel tricyclic compounds which can bind to FXR and act as modulators of the FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the uses of the compounds for the treatment of diseases and/or conditions mediated by FXR. The invention further provides a pharmaceutical composition containing the compound disclosed herein and a method of treatment of diseases and/or conditions mediated by FXR comprising administering the compound or the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.