Pyrimidine or pyridopyridone compound and application thereof
US10183941B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 31, 2016 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | May 31, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a pyrimidine or pyridopyridone compound as shown in formula (I) and an application thereof relating to the technical field of medicament preparation. The compound can selectively suppress cyclin-dependent kinases (Cdks) CDK4 and CDK6 with almost no suppression of the activity of the kinase CDK2. Thus, the compound can be used for various diseases caused by cell cycle control disorders involving CDK4 and CDK6, and particularly in the treatment of malignant tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.