Thienopyrroles as histone demethylase inhibitors
US10183952B2 · kind B2 · utility
2Cited by
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28Claims
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Key dates
| Filing date | Sep 4, 2015 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Sep 24, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application relates to thienopyrrole derivatives, compounds of Formulas (I) and (Ia), wherein R, R1, R2 and R3 are as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. The compounds of the application can be useful for inhibiting KDM1 and the prevention and/or treatment of cancer, infectious disease, or a disease characterized by aberration of cellular energy metabolism, e.g., obesity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.