Polynucleotides encoding bispecific EGFR/IGF-IR binding molecules
US10183987B2 · kind B2 · utility
7Cited by
65References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 23, 2017 |
| Grant date | Jan 22, 2019 |
| Priority date | — |
| Expiry date | Aug 23, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to bispecific molecules comprising an EGFR binding domain and a distinct IGFIR binding domain for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and vectors comprising the polynucleotides encoding the innovative proteins. Exemplary bispecific molecules include antibody-like protein dimers based on the tenth fibronectin type III domain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.