Transcriptional signature for chlamydial pelvic inflammatory disease

US10184152B2 · kind B2 · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Catherine O'Connell · Austin, US
• Toni Darville · Chapel Hill, US
• Xiaojing Zheng · Croton-on-Hudson, US

Key dates

• Filing date: Apr 16, 2015
• Grant date: Jan 22, 2019
• Expiry date: Apr 16, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods are provided herein for determining the likelihood that a subject, such as an asymptomatic subject, has chlamydial pelvic inflammatory disease. In some embodiments, the method can determine the likelihood that a pharmaceutical agent is effective for treating a subject that has chlamydial pelvic inflammatory disease. In other specific non-limiting examples, the method predicts endometritis and elevated pathogen burden. The subject is a female, such as a human female.