Patent · US Active

Intra-operative molecular imaging

US10188297B2 · kind B2 · utility

0Cited by
10References
20Claims
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Assignee

Inventor

Key dates

Filing dateFeb 29, 2016
Grant dateJan 29, 2019
Priority date
Expiry dateApr 7, 2036

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16H50/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, an applicator for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.