Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone
US10188639B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 15, 2015 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Jan 15, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/427
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides enantiopure deuterium-enriched pioglitazone, pharmaceutical compositions, and methods of treating neurological disorders, cancer, respiratory disorders, metabolic disorders, and other disorders using enantiopure deuterium-enriched pioglitazone. A preferred aspect of the invention provides methods of treating Alzheimer's disease, non-small cell lung cancer, hepatocellular carcinoma, and chronic obstructive pulmonary disease using enantiopure deuterium-enriched pioglitazone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.