Dual-modality imaging probe for combined localization and apoptosis detection of stem cells
US10188752B2 · kind B2 · utility
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Key dates
| Filing date | Aug 4, 2017 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Aug 4, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A ferumoxytol-based dual-modality imaging probe for long-term stem cell tracking through MRI and early diagnosis of cell apoptosis through simultaneous fluorescence imaging is provided. Specifically, a ferumoxytol-based dual-modality imaging probe is provided with enhanced T2* relaxivity for tracking stem cells through magnetic resonance imaging and detecting apoptotic stem cells through fluorescence imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.