Pyrazolyl-substituted pyridone compounds as serine protease inhibitors
US10189810B2 · kind B2 · utility
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66Claims
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Key dates
| Filing date | Sep 17, 2015 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Sep 17, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are provided inter alia pyrazolyl-substituted pyridone compounds, which exhibit biological activity, e.g., inhibitory action, against serine proteases, including thrombin and various kallikreins. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of serine proteases, including thrombin and various kallikreins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.